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NanoSIMS 50L

Microsonda SIMS para el análisis isotópico y de elementos de traza a alta resolución espacial
El NanoSIMS 50L es una microsonda de iones exclusiva que optimiza el rendimiento del análisis SIMS a una resolución lateral alta. Se basa en un diseño óptico coaxial del haz de iones y la extracción de iones secundarios, y en un analizador de masa del sector magnético original con recolección múltiple.
  • Descripción general de producto +

    El NanoSIMS 50L ofrece métricas de rendimiento clave simultáneas que solo se pueden obtener individualmente con cualquier otro instrumento o técnica conocida:
    • Alta resolución espacial de análisis (hasta 50 nanómetros)
    • Alta sensibilidad (ppm en imágenes de elementos)
    • Alta resolución de masa (M/dM),
    • Adquisición paralela de siete masas
    • Adquisición rápida (modo CC, no pulsado)
    • Análisis de muestras eléctricamente aislantes sin problema.
    Y gracias a las mejoras recientes, ahora se puede lograr la reproducibilidad de la relación de isótopos de algunas décimas de permil.

    Campos de aplicaciones ampliados


    El NanoSIMS 50L abre nuevas posibilidades para acoplar la identidad filogenética (con FISH o El-FISH) y la función metabólica (utilizando el indicador de isótopos estables) de células individuales en estudios de comunidades microbianas mixtas del medio ambiente.

    Biología celular:
    La resolución de 50 nm y las capacidades de relación isotópica del NanoSIMS 50L permiten la medición intracelular de acumulaciones y flujos de moléculas marcadas con isótopos estables

    Geología y ciencia espacial:
    El NanoSIMS 50L permite mediciones isotópicas y elementales precisas de áreas de submicrones profundas, granos o inclusiones de partículas de polvo interplanetarias, meteoritos y secciones minerales. Trabajando en múltiples configuraciones de copa Faraday y con un tamaño de punta de unos cuantos ?m, ofrece mediciones de relación de isótopos con precisión y reproducibilidad externa de hasta unas décimas de permil.

    Investigación de materiales:
    Gracias a su alta sensibilidad a alta resolución de masa (sin interferencia de masa), el NanoSIMS 50L permite obtener imágenes y cuantificación de elementos traza (adulterantes) con una resolución lateral SIMS de 50 nm, incluso en materiales eléctricamente aislantes. Todos los elementos, excepto los gases nobles, son accesibles, desde el hidrógeno hasta el plutonio.

    El NanoSIMS 50L fue diseñado originalmente por Pr. G. Slodzian, Universidad de París Sud, Francia.
  • Vea lo que puede hacer el NanoSIMS +

  • Descargar documentación +

  • Usuarios de NanoSIMS alrededor del mundo +

    Below are links to some of our NanoSIMS Users
    If your site is not listed and you would like to appear on this page, please contact

    Stanford Nano Shared Facilities (SNSF), CA, USA
    NSF provides shared scientific instrumentation, laboratory facilities, and expert staff support to enable multidisciplinary research and educate tomorrow’s scientists and engineers.

    NASA, Astromaterials Research & Exploration Science, Houston TX, USA
    The ARES scientists are dedicated to astromaterials research (meteorites, cosmic and interplanetary dust, solar wind, and lunar rocks), exobiology & organic geochemistry. They use a NanoSIMS 50L to uncover insights on processes of early solar system and stellar evolution.

    Chalmers University of Technology
    The NanoSIMS 50L in Gothenburg is the first of these instruments in Scandinavia. The NanoSIMS is suitable for a wide variety of applications such as grain boundary analysis, characterization of stress corrosion cracking, sub-cellular drug/peptide imaging and nitrogen fixation studies in bacteria.

    UPFL: Université Polytechnique Fédérale de Lausanne
    Laboratory for Biological Geochemistry LGB. Established in 2012, the LBG currently consists of about 15 Senior Scientists, Postdocs, PhD- and Master students working on research projects at the interface between isotope geochemistry, mineralogy and biology.

    TUM: Technische Universität München, Germany
    Research Department Ecology and Ecosystem Management. Soil is the focal and connecting link between the information, matter and energy cycles of the hydrogeosphere and the atmosphere. Soil organic matter, clay sized particles and iron oxides are the most important reactants in soils building a complex physico-chemical interface. (…)

    Helmholtz Centre for Environmental Research – UFZ Leipzig
    Department of Isotope Biogeochemistry.
    What is the role of biogeochemical processes in the functionality of sustainably managed ecosystems? How can stable isotope readings assist the understanding of the fate of chemicals in anoxic environments such as soil-aquifer systems, freshwater and deep-sea sediments and bioreactors? (…)

    CalTech Center for Microanalysis, USA
    The Center for Microanalysis at Caltech houses a NanoSIMS 50L and an IMS 7f-GEO, providing expertise for microanalysis of geological, meteoritic and synthetic materials. Research projects carried out at CCM are most varied, ranging from cosmochemistry to experimental studies on climate change, geochronology, in-situ studies of microbial communities, materials science engineering...

    Center for NanoImaging, Brigham and Women's Hospital
    Our mission is to extend multi-isotope imaging mass spectrometry – or MIMS – to new areas of biology and biomedical research, including with human translational studies conducted at the Brigham and Women’s Hospital and collaborating medical centers.

    Washington University in Saint Louis, MI, USA
    The Laboratory for Space Sciences at Washington University received the first NanoSIMS in 2000. Research projects cover presolar grains, interplanetary dust particles, meteorite geochemistry etc.

    Utrecht University, Netherlands
    Since summer 2013 Utrecht University hosts the Dutch national facility for high-resolution in situ isotope and element analysis of natural materials, supporting research in biogeochemistry and (microbial) ecology, paleo-environmental and climate reconstructions, planetary and solid earth sciences.
    > Watch video on NanoSIMS

    Manchester University, School of Materials, UK
    The NanoSIMS 50L is a major component of the Multi-Disciplinary Characterisation Facility, and is applied across a wide range of projects in advanced materials research, geological investigations of interest to the nuclear,oil and gas sectors, as well as the study of extra-terrestrial materials, but also tracing biochemical processes in microbes and plants.

    Max Planck Institut, Bremen, Germany

    The Max Planck Institute for Marine Microbiology of Bremen hosts the first NanoSIMS dedicated to environmental microbiology.

    Leibniz Institute for Baltic Sea Research (IOW), Warnemünde, Germany
    The NanoSIMS 50L at IOW is applied to a wide range of research fiels from microbiology and medicine to particle analysis and soil science.

    Environmental Molecular Science Laboratory, Richland, WA, USA
    EMSL, a national scientific user facility at Pacific Northwest National Laboratory has been equipped with a NanoSIMS 50L model since 2011.
    > Watch video on Air particle research at EMSL

    Faculty of Life Science, University of Vienna, Austria
    Inaugurated in February 2010, the NanoSIMS 50L lab is located within the Core Facility for Advanced Isotope Research. Under leadership from Michael Wagner, the Department of Microbial Ecology is one of the world leading center for single cell microbiology and the study of microorganisms in selected ecosystems.

    Institut Curie, Orsay, France
    Analytical Imaging of the Cell by Secondary Ion Mass Spectroscopy (SIMS microscopy). Introduction: "Of the various analytical methods developed in microscopy during the latter half of the century, SIMS imaging is probably one of the most powerful and sophisticated. Originally introduced..." Link to full article.

    Physical Research Laboratory, India
    Known as the cradle of Space Sciences in India, the Physical Research Laboratory (PRL) was founded in 1947 by Dr. Vikram Sarabhai. As a unit of the Department of Space, Government of India, PRL carries out fundamental research in select areas of Physics, Space & Atmospheric Sciences, Astronomy, Astrophysics & Solar Physics, and Planetary & Geosciences.

    Centre for Microscopy, Characterization & Analysis, UWA, Perth, Autralia
    Established in 1970, the CMCA provides essential teaching and research infrastructure in ion, electron, laser and light microscopy and microanalysis to universities, goverment of Western Australia and local industry. It is now home to two CAMECA ion probes, the NanoSIMS 50 installed in 2003 and the more recently acquired IMS 1280.

    LIST, Luxembourg institute of Science and Technology
    The Luxembourg Institute of Science and Technology (LIST) is a mission-driven Research and Technology Organisation (RTO) that develops advanced technologies and delivers innovative products and services to industry and society.

    Max Planck Institute for Chemistry, Cosmochemistry Department, Mainz, Germany
    The Cosmochemistry Department consists of several groups of scientists and technical personnel whose research interests and activities span a wide variety of fields in cosmochemical and space sciences. Many abstracts in the astrophysics field, downloadable in pdf format.

    The Department of Materials, University of Oxford, UK
    The CAMECA NanoSIMS 50 is an ultra high resolution chemical imaging facility combining the sensitivity of a dynamic SIMS with a lateral resolution of about 100nm. Our machine was delivered in August 2002 and is used on a very wide range of projects in the analysis of metallic, semiconducting, polymeric and biological materials....

    Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie (IMPMC)
    The IMPMC is particularly notable in its multidisciplinary approach. This means most topics are studied by researchers from different backgrounds—in physics, Earth science or biology. Experimental platforms, technical know-how and scientific expertise are all used to conduct research on the interactions between the living world (including bacteria) and the mineral world.

    Lawrence Livermore National Laboratory, California, USA
    Biology, materials, space sciences...
  • Software +

    • WinCurve dataprocessing sofware

      Desarrollado específicamente para instrumentos SIMS de CAMECA, WinCurve ofrece potentes capacidades de procesamiento y visualización de datos en un entorno fácil de usar.

      Seguir leyendo

    • WinImage Software
      WinImage II

      Desarrollado específicamente para los instrumentos SIMS de CAMECA, WinImage II ofrece potentes capacidades de visualización, procesamiento e impresión de imágenes en un entorno de Windows? para PC Entorno.

      Seguir leyendo

    • APM Software

      La medición automática de partículas (APM) es una herramienta de software de CAMECA que permite el filtrado rápido de millones de partículas, la detección de partículas y la caracterización isotópica.

      Seguir leyendo

  • Publicaciones de NanoSIMS +

    Se puede descargar una hoja de cálculo de Excel que compila artículos de investigación científica con datos de NanoSIMS. Los artículos están ordenados por las principales aplicaciones de la siguiente manera y se pueden buscar fácilmente con las funciones de búsqueda de palabras de Excel:

    • Partículas atmosféricas/aerosoles
    • Biomineralización/Paleoclima
    • Biología celular
    • Microbiología ambiental
    • Geología/Medio ambiente
    • Geocronología
    • Paleobiología/Evolución
    • Cosméticos y farmacología
    • Ciencias planetarias
    • Plantas
    • Suelo
    • Materiales
    • Instrumentación/Metodología
    Descargue la hoja de cálculo aquí: Compilación de artículos científicos de NanoSIMS.

    No dude en ponerse en contacto con nosotros en si no puede tener acceso a los archivos PDF por su cuenta. ¡También puede enviarnos cualquier referencia, pdf y suplemento que falte!
  • Kits de actualización +


    RF-plasma O-: High brightness O- primary ion source
    Replaces the duoplasmatron O- ion source. The higher brightness of the RF-plasma ion source permits to obtain similar O- beam density and lateral resolution as with the Cs+ source.

    D1 5-Slits_NS: Five D1 Aperture Diaphragm Slit
    Objective/immersion lens aperture strip increases the flexibility by increasing the diameter choice from 4 to 5 sizes.

    EXLIE Pre-implant_NS: Extreme low impact energy
    Ultra Low energy (25-500eV) sample bombardment allows pre-implantation/cleaning without consuming top surface of ultrathin samples.

    High Current Column_NS: High current primary ion column
    Allows Larger maximum Cs+ beam current (up to 20nA instead of a few nA).
    Using larger current permits to use multiple FCs instead of EM and improve isotope ratio reproducibility.


    Pfeiffer Turbo: Replacement of the three turbomolecular pumps
    Replace the three turbomolecular Varian/Agilent pumps by equivalent Pfeiffer models with excellent reliability.

    Load-lock Productivity Enhancement: Replacement of the standard turbopump if the load-lock
    For laboratories requiring unscheduled loadings and fast analysis, the standard 80 l/s turbopump of the load-lock can be replaced by a 300 l/s turbomolecular pump. The time needed to reach 1 E-6mbar in the load-lock is then typically reduced by x3 from ~120 min. to ~40 min.


    EM Preamplifier Gen2_NS: Five new EM preamplifier-discriminators
    Improvement of electronic ion pulse amplification for ion counting.
    More reliable settings and adjustments of discriminator/threshold for more reproducible isotopic ratios.

    Internal Multico Gen2_NS: New internal Multicollection
    Improved reliability, less short-circuits and blockages due to moveable cables.

    Low Noise Preamplifier_NS: Multico Geo Faraday : low noise preamplifier for FC#1
    Precise FC-EM isotope ratios.
    Lower noise/background for the Faraday cup resulting in better reproducibility and larger current detection range in FC.

    Multico Triple Faraday_NS: Multicollection triple Faraday
    Three FCs instead of one.
    Permits to measure isotopic ratios in multiple FCs with sub-permil reproducibility, generally recorded with higher (a few nA) and µm spot.

    NMR H/D_NS: Additional NMR probe for Hydrogen
    Stability of low mass spectrum lines.
    A third, dedicated NMR probe is added and improves the stability of analyzer magnetic field for high reproducibility on H ratios.


    Optical Microscope Gen2_NS: Improved Optical Microscope
    Replacement of illumination and optical microscope for more uniform lighting, digital camera, better resolution, numerical zoom.

    SED_NS: Secondary Electron Detector
    Secondary electron imaging for localization of small particles and good contrast to complement SIMS imaging.


    32b_Acquisition Board_NS: 32 bits counting board
    Replaces 16bit former version and is necessary for remote control through the internet using Team Viewer.
    No more saturation on SIMS images, faster scanning for less charging problems.


    PC automation_NS: PC Windows Control Upgrade
    The SUN system is no more supported and replaced by a PC Windows automation.
    New functions available under PC version.

    Software Version Update_NS: Updated Software version
    Latest PC automation version for removal of problems, new functions, and also required for some upgrades.

    Control Duplication_NS: Duplication of NanoSIMS control
    Control of the instrument from a separate operator room (<15 m), CAMECA designed keypad in both rooms.
    Allows optimized operation comfort (reduced noise, separate T°C control)

    Additional WinImage II_NS: Additional 64bit WinImage II Off-line PC Software Licence
    Image processing of SUN and PC data. Dongle for Multiple users.


    DUO Auto Valve_NS: Automation of Duoplasmatron leak valve
    Allows closing the leak valve at the end of unattended acquisition when using the duoplasmatron for longer use of duo source between dismounting for cleaning.

    Full MDA_NS: Aperture and Hexapole Automation
    Automation of slits & apertures for improvement of reproducibility, access by lower level users, chaining of cleaning/acquisition, comfort of use. 


    Sample-holders_Shuttles_NS: List of the sample-holders and the shuttles available at this link.
    Please contact the after-sales service for orders.

    Magnetic Transfer Rod:  Two magnetic transfer rods
    Transfer of the shuttle with its sample holder from the load-lock onto the analysis stage.

    You may also check the software versions available for your instrument.

    Don't hesitate to contact your local agent or the CAMECA sales department for more information.